The purpose of the present article is to share with psychologists and educators the integration proposed by several authors between what is known about the brain and the process of learning as it goes on in schools. Due to the developement of neurophysiological techniques during the recent decades, particularly imaging, an important advance in the knowledge of the functioning of the neuroendocrine system and brain machenisms has been evidenced. This has permitted the posing of certain principles as to the cerebrum's optimum state for learning. The background and development of the ideas related to brain based learning are reviewed.The main contributions can be found in the development of the concept of cerebral plasticity, significant learning, the effect of enriched early environment, the effect of nutrition and water, and the innate temporal rythms of living organisms which are influential on attention and focusing. The article ends with a summary of the most important principles suggested by Caine, Caine adn Crowell (1999) on brain based learning.
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